Cancer-Related Fatigue
Supervised, multimodal exercise is shown to be an
effective intervention against cancer-related fatigue
over and above pharmaceutical treatments.1
Cancer-Related Fatigue (CRF) is a distressing, persistent and subjective sense of physical, emotional and/or cognitive exhaustion related to cancer or cancer treatment that is not proportional to activity engaged in during the day and interferes with everyday functioning.

CRF is one of the most disabling, distressing, unfortunate and common symptoms that individuals with cancer can face, with up to 80 to 90 percent reporting CRF2.  Unfortunately, CRF can persist for years.3 Most individuals consider CRF a symptom that must be tolerated and more than one-half of patients will not discuss it with their providers.4 CRF can impact physical health and functioning and may cause a significant financial burden by decreasing the ability to work.2
Treating CRF
For adults with cancer, the evidence for rehabilitation and physical activity to decrease fatigue has grown. Home-based, low-impact exercise or physical activity can lessen fatigue for men with prostate cancer undergoing ADT or radiation, and individuals with lymphoma ovarian or breast cancer.5

Researchers found in a large majority of meta-analyses, an overall significant, positive impact of engaging in exercise to reduce the symptoms of CRF. Fuller and colleagues concluded being more active from diagnosis throughout the cancer journey will improve outcomes. Unfortunately, few individuals (with or without cancer) follow the recommended guidelines to exercise at least 150 minutes per week. With community-based cancer rehabilitation, individuals with cancer have the opportunity to work with certified professionals to supervise and develop their individualized exercise plan for better success.
Download the Cancer-Related Fatigue Fact Sheet here.

ReVital is a Leader in Cancer Rehabilitation

ReVital’s cancer rehabilitation therapists have been specially trained to prescribe effective treatment plans to help reduce CRF cancer-related fatigue in individuals affected by all cancer types. Our therapists are a valuable part of the cancer care team, and can help to decrease symptom burden and improve quality of life.

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  1. Mustian KM, Alfano CM, Heckler C, et al. Comparison of pharmaceutical, psychological, and exercise treatments for cancer-related fatigue: a meta-analysis. JAMA oncology. 2017;3(7):961-968.
  2. Hofman M, Ryan JL, Figueroa-Moseley CD, Jean-Pierre P, Morrow GR. Cancer-related fatigue: the scale of the problem. The oncologist. 2007;12(Supplement 1):4-10.
  3. Bower JE, Ganz PA, Desmond KA, et al. Fatigue in long‐term breast carcinoma survivors: a longitudinal investigation. Cancer. 2006;106(4):751-758.
  4. Luthy C, Cedraschi C, Pugliesi A, et al. Patients’ views about causes and preferences for the management of cancer-related fatigue—a case for non-congruence with the physicians? Supportive Care in Cancer. 2011;19(3):363-370.
  5. Schmitz KH, Courneya KS, Matthews C, et al. American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Medicine & Science in Sports & Exercise. 2010;42(7):1409-1426.
  6. Fuller JT, Hartland MC, Maloney LT, Davison K. Therapeutic effects of aerobic and resistance exercises for cancer survivors: a systematic review of meta-analyses of clinical trials. Br J Sports Med. 2018;52(20):1311-1311.