The ReVital Cancer Rehabilitation Program was developed to help people affected by cancer prevent and/or restore life roles, build strength, stamina, physical function and mobility; and maintain/regain independence.



The goal of the ReVital Cancer Rehabilitation Research Program is to demonstrate the value of cancer rehabilitation in achieving the quadruple aim of better patient health and experience, and decreased total cost and clinician burden.

Current Research Initiatives

Under the guidance and direction of ReVital’s Director of Research, Mackenzi Pergolotti, Ph.D., OTR/L, our team is actively partnering with independent oncology practices and academic medical centers on a number of research initiatives aligned to value-based oncology care. Today, these include:

  • Building a prospective rehabilitation pathway for individuals with breast cancer and sarcomas
  • Incorporating cancer rehabilitation into a team-based geriatric oncology program
  • Examining the impact of clinical and patient-reported outcome measures
  • Implementing new outcomes measures in community rehabilitation centers

Do you have an idea for a future research study? Are you interested in learning more about collaborating with the ReVital research team? If so, please email Dr. Pergolotti: [email protected].

ACRM Pandemic Webinar Series
Mackenzi Pergolotti, PhD, OTR/L, Director of Research, ReVital proposes best practices for cancer telerehab during the COVID-19 pandemic and beyond.
Presented as part of the ACRM Pandemic Webinar Series, May, 2020.

Key Publications

Below is a small sample of noteworthy papers and studies relevant to the field of cancer rehabilitation:

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  1. Cheville AL, Moynihan T, Herrin J, Loprinzi C, Kroenke K. Effect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer: A Randomized Clinical Trial. JAMA Oncol. 2019.
  2. Pergolotti M, Deal AM, Williams GR, et al. Older Adults with Cancer: A Randomized Controlled Trial of Occupational and Physical Therapy. Journal of the American Geriatrics Society. 2019;67(5):953-960.
  3. Schmitz KH, Ahmed RL, Troxel A, et al. Weight lifting in women with breast-cancer-related lymphedema. The New England journal of medicine. 2009;361(7):664-673.
  4. Schmitz KH. Incorporating Strength Training into Cancer Care: Translating PAL into the Strength After Breast Cancer Program. Obesity. 2017;25(S2):S32-S33.
  5. Pergolotti M, Williams GR, Campbell C, Munoz LA, Muss HB. Occupational Therapy for Adults With Cancer: Why It Matters. The oncologist. 2016;21(3):314-319.
  6. Cheville AL, Mustian K, Winters-Stone K, Zucker DS, Gamble GL, Alfano CM. Cancer Rehabilitation: An Overview of Current Need, Delivery Models, and Levels of Care. Physical medicine and rehabilitation clinics of North America. 2017;28(1):1-17.
  7. Alfano CM, Pergolotti M. Next-Generation Cancer Rehabilitation: A Giant Step Forward for Patient Care. Rehabil Nurs. 2018;43(4):186-194.
  8. Stubblefield MD, Kendig TD, Khanna A. ReVitalizing Cancer Survivors – Making Cancer Rehabilitation the Standard of Care. MD Advis. 2019;12(2):30-33.
  9. Pergolotti M, Lyons KD, Williams GR. Moving beyond symptom management towards cancer rehabilitation for older adults: Answering the 5W's. Journal of geriatric oncology. 2018;9(6):543-549.
  10. Mohile SG, Dale W, Somerfield MR, et al. Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology. Journal of Clinical Oncology. 2018;36(22):2326-2347.