Cancer-Related Fatigue
Supervised, multimodal exercise shown to be an
effective intervention against cancer-related fatigue
Cancer-Related Fatigue is a distressing, persistent and subjective sense of physical, emotional and/or cognitive tiredness or exhaustion related to cancer or cancer treatment that is not proportional to recent activity and interferes with usual functioning.1

Studies show that it affects the vast majority of cancer patients (70 to 100%) but that as few as 15% of patients with CRF receive treatment or advice about management of their fatigue. It can persist for months or even years after treatment is completed. Since it affects patients in so many ways, it can reduce the chance of cure by negatively impacting compliance and the desire to continue with treatment.
Treating CRF

In the past, clinicians often recommended rest for patients with CRF. However, exercise has been demonstrated to be effective in reducing fatigue and improving functional capacity.
In the past five years, there has been a considerable amount of research demonstrating that exercise has a positive impact on reducing cancer-related fatigue.
  • A 2018 meta-analysis of the effect of exercise on CRF concluded that: exercise has a large effect on CRF in cancer survivors. Aerobic interventions with high adherence have the best result. 2
  • A 2017 study on the effect of aerobic exercise on cancer-related fatigue stated that: there was a significant reduction in cancer-related fatigue BFI score (P < 0.0001,) 3
  • A 2014 study on the effect of scheduled exercise on cancer-related fatigue in women with early breast cancer reports: “the findings suggest that generally recommended physical activity levels of 150 minutes/week of moderate to vigorous physical activity is enough to sufficiently relieve cancer-related fatigue and restore physical fitness and activity levels.4
Download our Cancer-Related Fatigue Fact Sheet to learn the latest findings about CRF and how cancer rehabilitation can benefit your patients.

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ReVital is a Leader in Cancer Rehabilitation

ReVital cancer rehabilitation therapists have been specially trained to prescribe effective treatment plans that can help to reduce CRF in people with all cancer types. Our therapists can be a valuable part of the cancer care team, helping to improve the quality of life for patients, increase compliance and thereby improve outcomes.

1. J Natl Compr Canc Netw. 2015 Aug;13(8):1012-39.,
2. Neuropsychiatr Dis Treat. 2018; 14: 479–494. Is Neuropsychiatry missing the y? Published online 2018 Feb 9. doi: 10.2147/NDT.S150464.
3. Indian J Palliat Care. 2017 Oct-Dec; 23(4): 355–361. doi: 10.4103/IJPC.IJPC_65_17
4. ScientificWorldJournal. 2014; 2014: 271828. Published online 2014 Jan 19. doi: 10.1155/2014/271828