This study found that not only did CIPN increase fall risk, but that CIPN-related falls were associated with increased utilization of health care resources.4 A 2017 study in the Journal of Clinical Oncology examined the prevalence of CIPN in 512 women with cancer. It found that almost 50 percent still experienced symptoms up to six years post-treatment with symptomatic survivors being almost twice as likely to fall when compared to asymptomatic counterparts.5
With a $30,000+ average cost per fall injury, these numbers can have a substantial impact on both patients’ quality of life and individual and societal cost burdens.6
CIPN may cause disruptions in the medical treatment schedule, including chemotherapy dose reductions and/or early discontinuation, thus potentially compromising patient outcomes and survival.7
A 2018 phase III randomized control trial found that engaging in exercise appears to reduce CIPN symptoms in adults who receive taxane-, platinum- or vinca alkaloid-based chemotherapy.
For the 355 participants, exercise significantly reduced their symptoms of hot/coldness in hands/feet (-0.46 units, p = 0.045), and numbness and tingling (-0.42 units, p = 0.061) compared to the control group. The results were strongest among an older population.8 Another study of individuals with multiple cancer types with CIPN, tested multimodal exercise and found an improvement in balance, mobility and quality of life.9
- In another exercise-based study, 50 women with breast cancer who were experiencing CIPN were given a 10-week, home-based exercise program. Following 10 weeks of exercise, the women reported experiencing less unpleasant skin sensations, feeling less abnormally sensitive to touch and a reduction in pain coming on suddenly in bursts for no apparent reason (p =0.05).
- By engaging in the recommended 150 minutes of physical activity, a large registry study found that adults with cancer were more likely to have lessened CIPN symptoms and have a better quality of life than adults who were less active. 10
Learn more about how the ReVital Cancer Rehabilitation program can help improve patient outcomes, facilitate improved compliance with chemotherapy and reduce treatment costs.